Animal StudyEffects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive ratsMHID-7818899PMID: 352644922022Experimental AnimalsKohei Kawakami, Hiroyuki Matsuo, Takaya Yamada, Ken-ichi Matsumoto, Daigoro Sasaki, Masato NomuraHydrogen-rich water (HW) has been suggested to possess antioxidant properties of value in treatments of lifestyle diseases and for prevention of latent pathologies. To date, the potential benefits of HW against the deleterious effects of excessive salt intake and hypertension have not been investigated. Here, we first examined the effects of HW or HW supplemented with 0.1% ascorbic acid (HWA) on s
Clinical TrialHighlightedThe effect of a low dose hydrogen-oxygen mixture inhalation in midlife/older adults with hypertension: A randomized, placebo-controlled trialMHID-1269854PMID: 362782212022Frontiers in PharmacologyBoyan Liu, Xue Jiang, Yunbo Xie, Xiubin Jia, Jiashuo Zhang, Yazhuo Xue, et al.Objective: To explore the effect of a low-dose hydrogen–oxygen (H2-O2) mixture inhalation in midlife/older adults with hypertension. Methods: This randomized, placebo-controlled trial included 60 participants with hypertension aged 50–70 years who were randomly divided into Air group (inhaled placebo air) or H2-O2 group [inhaled H2-O2 mixture (66% H2/33% O2)]. Participants in both groups were tre
