Plant StudyHighlightedHydrogen gas acts as a novel bioactive molecule in enhancing plant tolerance to paraquat-induced oxidative stress via the modulation of heme oxygenase-1 signalling systemMHID-6657679PMID: 230947982012Plant, Cell and EnvironmentQijiang Jin, Weiti Cui, Bin Han, Yanjie Xie, Kaikai Zhu, Wenbiao ShenHydrogen gas (H2) was recently proposed as a novel antioxidant and signalling molecule in animals. However, the physiological roles of H2 in plants are less clear. Here, we showed that exposure of alfalfa seedlings to paraquat stress increased endogenous H2 production. When supplied with exogenous H2 or the heme oxygenase-1 (HO-1)-inducer hemin, alfalfa plants displayed enhanced tolerance to oxida