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Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection

MHID-7349011PMID: 286696542017Journal of Stroke and Cerebrovascular Diseases

Hirohisa Ono, MD, Yoji Nishijima, MD, Shigeo Ohta, PhD, Masaki Sakamoto, MD, Kazunori Kinone, MD, Tohru Horikosi, MD, et al.

Background: Molecular hydrogen (H2) acts as a therapeutic antioxidant. Inhalation of H2 gas (1-4%) was effective for the improvement of cerebral infarction in multiple animal experiments. Thus, for actual applications, a randomized con- trolled clinical study is desired to evaluate the effects of inhalation of H2 gas. Here, we evaluate the H2 treatment on acute cerebral infarction. Methods: Throu