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Clinical TrialAnimal StudyHighlighted

A novel intervention of molecular hydrogen on the unbalance of the gut microbiome in opioid addiction: Experimental and human studies

MHID-3437190PMID: 391167822024Biomedicine & Pharmacotherapy

Bing Xie, Yong Wang, Yun Lu, Mengmeng Wang, Rongji Hui, Hailei Yu, et al.

The gut-brain axis mediates the interaction pathway between microbiota and opioid addiction. In recent years, many studies have shown that molecular hydrogen has therapeutic and preventive effects on various diseases. This study aimed to investigate whether molecular hydrogen could serve as pharmacological intervention agent to reduce risks of reinstatement of opioid seeking and explore the mechan

Animal StudyHighlighted

Different effects of hydrogen‑rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status

MHID-9053506PMID: 355085712022Scientific Reports

Fei Xie, Xue Jiang, Yang Yi, Zi‑Jia Liu, Chen Ma, Jin He, et al.

The potential for preventive and therapeutic applications of H2 have now been confirmed in various disease. However, the effects of H2 on health status have not been fully elucidated. Our previous study reported changes in the body weight and 13 serum biochemical parameters during the six-month hydrogen intervention. To obtain a more comprehensive understanding of the effects of long-term hydrogen