Animal StudyHighlightedHydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbitsMHID-2777514PMID: 225876642012BMC NeuroscienceZong Zhuang, Meng-liang Zhou, Wan-chun You, Lin Zhu, Chi-yuan Ma, Xue-Jun Sun, et al.Background: Increasing experimental and clinical data indicate that early brain injury (EBI) after subarachnoid hemorrhage (SAH) largely contributes to unfavorable outcomes, and it has been proved that EBI following SAH is closely associated with oxidative stress and brain edema. The present study aimed to examine the effect of hydrogen, a mild and selective cytotoxic oxygen radical scavenger, on
Animal StudyHydrogen is neuroprotective against surgically induced brain injuryMHID-1564427PMID: 221464272011Medical Gas ResearchJan M Eckermann, Wanqiu Chen, Vikram Jadhav, Frank PK Hsu, Austin RT Colohan, Jiping Tang, et al.Background: Neurosurgical operations cause unavoidable damage to healthy brain tissues. Direct surgical injury as well as surgically induced oxidative stress contributes to the subsequent formation of brain edema. Therefore, we tested the neuroprotective effects of hydrogen (H2) in an established surgical brain injury (SBI) model in rats. Materials and methods: Adult male Sprague - Dawley rats (w
