Scientific Articles

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HypothesisOpinion PieceHighlighted

Role of molecular hydrogen in obesity treatment: modulation of GLP-1, irisin, and PGC-1α for improved metabolism

MHID-6155704PMID: 402510252025Medical Gas Research

Nikola Todorovic, Jovan Kuzmanovic, Dejan Javorac, Sergej M Ostojic

The increasing prevalence of obesity and non-communicable diseases has become a major global health concern, contributing to significant morbidity and mortality rates. These conditions not only burden healthcare systems but also affect the individual’s quality of life worldwide. As these challenges continue to grow, there is a pressing need to explore treatment options that are effective, affordab

Clinical TrialHighlighted

Hydrogen-rich water upregulates fecal propionic acid levels in overweight adults

MHID-9342144PMID: 377341172023Nutrition

Darinka Korovljev Ph.D., Nikola Todorovic M.Sc., Marijana Ranisavljev M.Sc., Bogdan Andjelic M.Sc., Nebojsa Kladar M.D., Ph.D., Valdemar Stajer Ph.D., et al.

The intricate relationship between the gut microbiota, its metabolites, and human health has garnered significant attention in recent years because of its potential role in the development of many diseases [1]. Among the various metabolites produced by the microbiota, a group of organic acids, known as short-chain fatty acids (SCFAs), has emerged as key regulators of host energy metabolism. These

Animal Study

Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

MHID-4869388PMID: 316002562019PLoS ONE

Laura Bordoni, Rosita Gabbianelli, Donatella Fedeli, Dennis Fiorini, Ina Bergheim, Cheng Jun Jin, et al.

There is growing awareness within the scientific community of the strong connection between the inflammation in the intestine and the pathogenesis of Parkinson’s disease (PD). In previous studies we developed a PD animal model exposing pup rats to permethrin (PERM) pesticide. Here, we intended to explore whether in our animal model there were changes in gut permeability, fecal microbiota and hepat