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Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma

MHID-5043020PMID: 236615162013European Review for Medical and Pharmacological Sciences

M. Xiao, T. Zhu, T. Wang, F.-Q. Wen

Recent studies suggest that hydrogen has great therapeutic and prophylactic potential against organ injury caused by oxidative stress and inflammation. Here we investigated the effect of hydrogen-rich saline on airway inflammation and remodeling in a murine model of asthma. MATERIALS AND METHODS: Asthma was induced by ovalbumin (OVA) sensitization and challenge. Then mice were treated with normal