Animal StudyDaily inhalation of hydrogen gas has a blood pressure‑lowering effect in a rat model of hypertensionMHID-4743523PMID: 332440272020Scientific ReportsKazuhisa Sugai, Tomoyoshi Tamura, Motoaki Sano, Shizuka Uemura, Masahiko Fujisawa, Yoshinori Katsumata, et al.A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H2) improves blood pressure control in end-stage kidney disease. Herein, we examined whether H2 has a salutary effect on hypertension in animal models. We subjected 5/6 nephrectomised rats to inhalation of either H2 (1.3% H2 + 21% O2 + 77.7% N2) or control (21% O2 + 79% N2) gas mixture for 1 h per day. H2
Animal StudyHighlightedEffects of hydrogen-rich water on abnormalities in a SHR.Cg-Leprcp/NDmcr rat - a metabolic syndrome rat modelMHID-2760312PMID: 221460832011Medical Gas ResearchMichio Hashimoto, Masanori Katakura, Toru Nabika, Yoko Tanabe, Shahdat Hossain, Satoru Tsuchikura, et al.Background: Hydrogen (H2), a potent free radical scavenger, selectively reduces the hydroxyl radical, which is the most cytotoxic of the reactive oxygen species (ROS). An increase in oxygen free radicals induces oxidative stress, which is known to be involved in the development of metabolic syndrome. Therefore, we investigated whether hydrogen-rich water (HRW) affects metabolic abnormalities in th
