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Animal Study

Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF‑κB Inflammatory Pathway

MHID-0385819PMID: 358952452023Journal of Neuroimmune Pharmacology

Wan‑Chao Yang, Ting‑ting Li, Qiang Wan, Xin Zhang, Li‑Ying Sun, Yu‑Rong Zhang, et al.

Diabetes is an independent risk factor for stroke and amplifies inflammation. Diabetic stroke is associated with a higher risk of death and worse neural function. The identification of effective anti-inflammatory molecules with translational advantages is particularly important to promote perioperative neurorestorative effects. Applying molecular hydrogen, we measured blood glucose levels before a

Animal Study

Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

MHID-4869388PMID: 316002562019PLoS ONE

Laura Bordoni, Rosita Gabbianelli, Donatella Fedeli, Dennis Fiorini, Ina Bergheim, Cheng Jun Jin, et al.

There is growing awareness within the scientific community of the strong connection between the inflammation in the intestine and the pathogenesis of Parkinson’s disease (PD). In previous studies we developed a PD animal model exposing pup rats to permethrin (PERM) pesticide. Here, we intended to explore whether in our animal model there were changes in gut permeability, fecal microbiota and hepat