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Combating oxidative stress and inflammation in gentamicin-induced nephrotoxicity using hydrogen-rich water.

MHID-2726672PMID: 395318562024Tissue & cell

Cumaoglu MO, Makav M, Dag S, Uysal AY, Baser L, LeBaron TW, et al.

Gentamicin-induced nephrotoxicity primarily results from renal inflammatory cascades and increased oxidative stress. This study aims to examine the effects of hydrogen-rich water (HRW) on gentamicin-induced renal damage in rats. Thirty-two rats were equally divided into four groups, including control (no treatment), hydrogen, gentamicin, and gentamicin+hydrogen. At the end of one week, all animals