Clinical TrialHighlightedMolecular hydrogen exposure improves functional state of red blood cells in the early postoperative period: a randomized clinical studyMHID-8082099PMID: 362047842023Medical Gas ResearchAnna Vaycheslavovna Deryugina, Darya Andreevna Danilova, Yurii Dmitrievich Brichkin, Evgenii Vladimirovich Taranov, Evgenii Ivanovich Nazarov, Vladimir Viktorovich Pichugin, et al.Molecular hydrogen (H2) has been considered a preventive and therapeutic medical gas in numerous diseases. The study aimed to investigate the potential role of molecular hydrogen as a component of anesthesia in surgical treatment with cardiopulmonary bypass (CPB) of acquired valve defects on the functional state of red blood cells (RBC) and functional indicators of cardiac activity. This clinical
Clinical TrialObservational StudyHighlightedCombined Administration of Nitric Oxide and Hydrogen into Extracorporeal Circuit of Cardiopulmonary Bypass as a Method of Organ Protection during Cardiac SurgeryMHID-0894811PMID: 399679162023Sovremennye tehnologii v medicineV.V. Pichugin, A.V. Derugina, S.E. Domnin, A.S. Shirshin, S.A. Fedorov, S.N. Buranov, et al.The aim is to study the effect of combined introduction of nitric oxide and hydrogen into the extracorporeal circuit of cardiopulmonary bypass (CPB) for antioxidant activity and organ damage during cardiac surgery. Materials and Methods. The study included 91 patients who underwent heart surgery under CPB. The patients were randomized into 3 groups: group 1 comprised 30 patients (control); group
