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Observational Study

Successful treatment of myalgic encephalomyelitis/chronic fatigue syndrome using hydrogen gas: four case reports

MHID-3841687PMID: 379295122024Medical Gas Research

Shin-ichi Hirano, Yusuke Ichikawa, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by unexplained fatigue and malaise that persist for more than 6 months with neuropsychiatric symptoms, including slight fever, headache, weakness, impaired thinking, and depression. The onset and severity of these symptoms vary and reduce the quality of life as well as social, occupational, and personal activities of thos

Animal Study

Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota

MHID-6003573PMID: 364684152023CNS Neuroscience & Therapeutics

Qingqing Han, Yuanyuan Bai, Chunjing Zhou, Beibei Dong, Yingning Li, Ning Luo, et al.

Introduction: In our experiments, male wild-type mice were randomly divided into four groups: the sham, SAE, SAE + 2% hydrogen gas inhalation (H2), and SAE + hydrogen-rich water (HW) groups. The feces of the mice were collected for 16 S rDNA analysis 24 h after the models were established, and the serum and brain tissue of the mice were collected for nontargeted metabolomics analysis. Aim: Destru

Clinical TrialHighlighted

Hydrogen intake relieves alcohol consumption and hangover symptoms in healthy adults: a randomized and placebo-controlled crossover study

MHID-0754862PMID: 361246532022American Journal of Clinical Nutrition

Xiang Lv, Yuanfeng Lu, Guoyong Ding, Xiao Li, Xinxin Xu, Aihua Zhang, et al.

Background: Alcohol-induced hangover represents a significant, yet understudied, global hazard and a large socioeconomic burden. Objective: The aim of this study was to investigate the effects of hydrogen on relieving drinking and hangover symptoms in 20 healthy volunteers. Methods: In this pilot, randomized, double-blinded, placebo- controlled, matched, crossover interventional trial, participan