Animal StudyHighlightedProtective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary FibrosisMHID-4298510PMID: 285227972017Medical Science MonitorWen-Wen Dong, Yun-Qian Zhang, Xiao-Yan Zhu, Yan-Fei Mao, Xue-Jun Sun, Yu-Jian Liu, et al.Background: Fibrotic change is one of the important reasons for the poor prognosis of patients with acute respiratory distress syndrome (ARDS). The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis. Material/Methods: Male ICR mice were divided randomly into 5 groups: Control, LPS-treated p
Animal StudyHydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in ratsMHID-0745319PMID: 286562162017Molecular Medicine ReportsJing Yang, Shujing Wu, Liqun Zhu, Jingjing Cai, Lu FuCardiac fibrosis induced by sustained pressure overload contributes to heart failure. Oxidative stress serves an important role in cardiac remodeling and heart failure independent of etiological factors. The application of hydrogen as an antioxidant is a novel concept in disease treatment, however no studies as present have investigated the effects of hydrogen on cardiac fibrosis. In the present s
