Scientific Articles

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Clinical TrialObservational StudyHighlighted

Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial

MHID-6130347PMID: 357749172022Health Psychology Research

Ana Belén Fernández-Serrano, Francisco José Moya-Faz, Cesar Augusto Giner Alegría, Juan Carlos Fernández Rodríguez, Jose Francisco Soriano Guilabert, Martín del Toro Mellado

Research suggests that inflammation is an important mediator in the pathophysiology of anxiety disorders. In addition, women are more likely to develop an anxiety and depression disorder, in comorbidity with a wide spectrum of diseases related to the immune system. In recent years, hydrogen-rich water has emerged as a promising therapeutic strategy to prevent and intervene in stress-related disord

In VitroHighlighted

Molecular hydrogen protects against oxidative stress‑induced RAW 264.7 macrophage cells through the activation of Nrf2 and inhibition of MAPK signaling pathway

MHID-35801392020Molecular & Cellular Toxicology

Rahima Begum, Cheol‑Su Kim, Ailyn Fadriquela, Johny Bajgai, Xingyu Jing, Dong‑Heui Kim, et al.

Background: Oxidative stress is involved in the development of many inflammatory, metabolic and aging diseases. Objective: In this study we investigated, the protective effects of H2 on RAW 264.7 macrophage cell against LPS-and H2O2-induced oxidative stress by the inhibition of MAPK pathway and also activate the Nrf2 pathway. Results: Our results showed H2 increased the macrophage cell prolifera

Animal StudyHighlighted

Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction

MHID-5761446PMID: 246182602014Journal of Cellular and Molecular Medicine

Sanhu Zhao, Yanyong Yang, Wen Liu, Zhiqiang Xuan, Shouming Wu, Shunfei Yu, et al.

Recent studies showed that hydrogen can be used as an effective radioprotective agent through scavenging free radicals. This study was under- taken to evaluate the radioprotective effects of hydrogen on immune system in mice. H2 was dissolved in physiological saline using an apparatus produced by our department. Spleen index and histological analysis were used to evaluate the splenic structural da