Animal StudyHighlightedHydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stressMHID-5191051PMID: 281009592017Journal of InflammationShaoqing Yu, Chuanliang Zhao, Na Che, Lin Jing, Rongming GeBackground: It is well considered that reactive oxygen species (ROS) plays a prominent causative role in the development of allergic rhinitis (AR), and eosinophils cells as important allergic inflammatory cells contribute to elevating oxidative stress. Hydrogen, emerging as a novel antioxidant, has been proven effective in selectively reducing ROS in animals models of oxidative damage. We herein a
Animal StudyHighlightedPositive Effects of Hydrogen Water on 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis in NC/Nga MiceMHID-1117942PMID: 251770312014Biological & Pharmaceutical BulletinYang-Suk Yoon, Ma. Easter Joy Villarosa Sajo, Rosa Mistica Coles Ignacio, Soo-Ki Kim, Cheol-Su Kim, Kyu-Jae LeeAtopic dermatitis (AD) is a chronically relapsing, pruritic, eczematous skin disorder accompanying al- lergic inflammation. AD is triggered by oxidative stress and immune imbalance. In the present study, we in- vestigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that HW ameliorated DNCB-induced AD-like clinical
