Clinical TrialAnimal StudyHighlighted
MHID-5385411PMID: 291106152018Current Alzheimer Research
Kiyomi Nishimaki, Takashi Asada, Ikuroh Ohsawa, Etsuko Nakajima, Chiaki Ikejima, Takashi Yokota, et al.
Background: Oxidative stress is one of the causative factors in the pathogenesis of neurodegenerative diseases including mild cognitive impairment (MCI) and dementia. We previously reported that molecular hydrogen (H2) acts as a therapeutic and preventive antioxidant.
Objective: We assess the effects of drinking H2-water (water infused with H2) on oxidative stress model mice and subjects with MCI
Animal Study
MHID-0185761PMID: 252512202014PLoS ONE
Kenji Dohi, Brian C. Kraemer, Michelle A. Erickson, Pamela J. McMillan, Andrej Kovac, Zuzana Flachbartova, et al.
Traumatic brain injury (TBI) in its various forms has emerged as a major problem for modern society. Acute TBI can transform into a chronic condition and be a risk factor for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases, probably through induction of oxidative stress and neuroinflammation. Here, we examined the ability of the antioxidant molecular hydrogen given in drink
Animal StudyIn VitroHighlighted
MHID-7700658PMID: 174860892007Nature Medicine
Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi, Megumi Watanabe, Kiyomi Nishimaki, Kumi Yamagata, et al.
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H2) has potential as an antioxidant in preventive and therapeutic applications. We induced acute oxidative stress in cultured cells by three independent methods.
