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In VitroHighlighted

Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells

MHID-9934004PMID: 234482062013Medical Gas Research

Akio Iio, Mikako Ito, Tomohiro Itoh, Riyako Terazawa, Yasunori Fujita, Yoshinori Nozawa, et al.

Background: There is accumulating evidence that obesity is closely associated with an impaired free fatty acid metabolism as well as with insulin resistance and inflammation. Excessive fatty acid uptake mediated by fatty acid translocase CD36 plays an important role in hepatic steatosis. Molecular hydrogen has been shown to attenuate oxidative stress and improve lipid, glucose and energy metabolis