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Animal StudyChemical/Physicochemical StudyHighlighted

Molecular hydrogen: prospective treatment strategy of kidney damage after cardiac surgery

MHID-2226442PMID: 374635172023Canadian Journal of Physiology and Pharmacology

Barbora Kalocayova, Branislav Kura, Jana Vlkovicova, Denisa Snurikova, Norbert Vrbjar, Karel Frimmel, et al.

Cardiac surgery-associated acute kidney injury (CS-AKI) is a common postoperative complication, mostly due to increasing oxidative stress. Recently, molecular hydrogen (H2 gas), has also been applied to cardiac surgery due to its ability to reduce oxidative stress. We evaluated the potential effect of H2 application on the kidney in an in vivo model of simulated heart transplantation. Pigs underwe

Animal StudyHighlighted

Social Communication of Maternal Immune Activation-Affected Offspring Is Improved by Si-Based Hydrogen-Producing Agent

MHID-1698660PMID: 354927052022Frontiers in Psychiatry

Noriyoshi Usui, Kazumasa Matsumoto-Miyai, Yoshihisa Koyama, Yuki Kobayashi, Yukiko Nakamura, Hikaru Kobayashi, et al.

Maternal immune activation (MIA) is triggered by infection or autoimmune predisposition during pregnancy, and cytokines produced by MIA are transmitted through the placenta to the fetal brain, implicating at the onset risks and vulnerability for developmental and psychiatric disorders, such as autism spectrum disorder (ASD) and schizophrenia. To address these kinds of problem in child health, we h