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Clinical Trial

Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women

MHID-9868845PMID: 285605192018Irish Journal of Medical Science

D. Korovljev, T. Trivic, P. Drid, S. M. Ostojic

Background: Molecular hydrogen (H2) effectively treats obesity-related disorders in animal models, yet no studies have investigated the effectiveness and safety of H2 for improving biomarkers of obesity in humans. Aim: In this double blind, placebo-controlled, crossover pilot trial, we evaluated the effects of H2 intervention on body composition, hormonal status, and mitochondrial function in ten

Clinical TrialHighlighted

Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies

MHID-2481572PMID: 221466742011Medical Gas Research

Mikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito, Kinji Ohno

Background: Molecular hydrogen has prominent effects on more than 30 animal models especially of oxidative stress-mediated diseases and inflammatory diseases. In addition, hydrogen effects on humans have been reported in diabetes mellitus type 2, hemodialysis, metabolic syndrome, radiotherapy for liver cancer, and brain stem infarction. Hydrogen effects are ascribed to specific radical-scavenging