Ex VivoHighlightedMolecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: Novel cardioprotective interventionMHID-8457494PMID: 283509672017Canadian Journal of Physiology and PharmacologyMarek Zálešák, Branislav Kura, Ján Graban, Veronika Ledvényiová-Farkašová, Jan Slezak, Tatiana RavingerovaGeneration of free radicals through incomplete reduction of oxygen during ischemia/ reperfusion is well-described. On the other hand, molecular hydrogen (H2) reduces oxidative stress due to its ability to react with strong oxidants and easily penetrate cells by diffusion, without disturbing metabolic redox reactions. This study was designed to explore cardioprotective potential of hypoxic postcond
Animal StudyHighlightedHydrogen-Rich Saline Protects Myocardium Against Ischemia/Reperfusion Injury in RatsMHID-7407969PMID: 195968252009Experimental Biology and MedicineQIANG SUN, ZHIMIN KANG, JIANMEI CAI, WENWU LIU, YUN LIU, John H Zhang, et al.Protective effect of hydrogen (H2) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This study was designed to test the hypothesis that hydrogen-rich saline (saline saturated with molecular hydrogen), which is easy to use, induces cardioprotection against ischemia (30 min) and reperfusion (24 h) injury in rats. Adult male Sprague-Dawley rats underwent 30-min occlu