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The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction

MHID-7076048PMID: 283210092017Circulation Journal

Yoshinori Katsumata, Koichiro Homma, Masaru Suzuki, Shigeo Okuda

Background: Hydrogen gas inhalation (HI) reduced infarct size and mitigated adverse left ventricular (LV) remodeling in a rat model of acute myocardial infarction (AMI). We designed a prospective, open-label, rater-blinded clinical pilot study in patients experiencing ST-elevated MI (STEMI). Methods and results: The 20 patients with an initial diagnosis of STEMI were assigned to either an HI grou