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Literature ReviewHighlighted

Molecular Hydrogen in the Treatment of Respiratory Diseases

MHID-45792272025International Journal of Molecular Sciences

Dominika Zajac, Monika Jampolska, Piotr Wojciechowski

Molecular hydrogen is gaining increasing attention as an antioxidant, anti- inflammatory, and antiapoptotic agent. Once considered an inert gas, it reveals current therapeutic potential among others in inflammatory diseases, cancer, and sports medicine, among others. The present review aims to provide a consistent summary of the findings of the last twenty years on the use of molecular hydrogen in

Animal StudyHighlighted

Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma

MHID-5043020PMID: 236615162013European Review for Medical and Pharmacological Sciences

M. Xiao, T. Zhu, T. Wang, F.-Q. Wen

Recent studies suggest that hydrogen has great therapeutic and prophylactic potential against organ injury caused by oxidative stress and inflammation. Here we investigated the effect of hydrogen-rich saline on airway inflammation and remodeling in a murine model of asthma. MATERIALS AND METHODS: Asthma was induced by ovalbumin (OVA) sensitization and challenge. Then mice were treated with normal