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Animal Study

Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota

MHID-6003573PMID: 364684152023CNS Neuroscience & Therapeutics

Qingqing Han, Yuanyuan Bai, Chunjing Zhou, Beibei Dong, Yingning Li, Ning Luo, et al.

Introduction: In our experiments, male wild-type mice were randomly divided into four groups: the sham, SAE, SAE + 2% hydrogen gas inhalation (H2), and SAE + hydrogen-rich water (HW) groups. The feces of the mice were collected for 16 S rDNA analysis 24 h after the models were established, and the serum and brain tissue of the mice were collected for nontargeted metabolomics analysis. Aim: Destru