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Effects of hydrogen‑rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation

MHID-4748086PMID: 260479402015Journal of Translational Medicine

Song‑Xue Guo, Quan Fang, Chuan‑Gang You, Yun‑Yun Jin, Xin‑Gang Wang, Xin‑Lei Hu, et al.

Background: Early acute kidney injury (AKI) in severely burned patients predicts a high mortality that is multi-factorial. Hydrogen has been reported to alleviate organ injury via selective quenching of reactive oxygen species. This study investigated the potential protective effects of hydrogen against severe burn-induced early AKI in rats. Methods: Severe burn were induced via immersing the sha