Scientific Articles

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Clinical Trial

Inhalation of Hydrogen-rich Gas before Acute Exercise Alleviates Exercise Fatigue: A Randomized Crossover Study

MHID-0740382PMID: 386986242024International Journal of Sports Medicine

Gengxin Dong, Jianxin Wu, Yinglu Hong, Qian Li, Meng Liu, Guole Jiang, et al.

Hydrogen, as an antioxidant, may have the potential to mitigate fatigue and improve selected oxidative stress markers induced by strenuous exercise. This study focused on a previously unexplored approach involving pre-exercise inhalation of hydrogen-rich gas (HRG). Twenty-four healthy adult men first completed pre-laboratories to determine maximum cycling power (Wmax) and maximum cycling time (Tma

Animal StudyIn VitroHighlighted

A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases

MHID-1279019PMID: 372155682023Theranostics

Geru Tao, Feng Liu, Zhaokui Jin, Boyan Liu, Hao Wang, Daosheng Li, et al.

Background: Chronic liver diseases (CLD) frequently derive from hepatic steatosis, inflammation and fibrosis, and become a leading inducement of cirrhosis and hepatocarcinoma. Molecular hydrogen (H2) is an emerging wide-spectrum anti-inflammatory molecule which is able to improve hepatic inflammation and metabolic dysfunction, and holds obvious advantages in biosafety over traditional anti-CLD dru

Animal StudyIn VitroHighlighted

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

MHID-7700658PMID: 174860892007Nature Medicine

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi, Megumi Watanabe, Kiyomi Nishimaki, Kumi Yamagata, et al.

Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H2) has potential as an antioxidant in preventive and therapeutic applications. We induced acute oxidative stress in cultured cells by three independent methods.