Animal StudyHighlightedHydrogen-rich water improves endurance by reducing skeletal muscle oxidative stress and inflammatory responsesMHID-8967574PMID: 416411602026Frontiers in NutritionEika Mizuno, Tatsuhiro Sato, Kosuke Okada, Ikuru Miura, Junichi Shoda, Makoto Saito, et al.Introduction: Hydrogen-rich water (HRW) has been reported to reduce oxidative stress, suppress exercise fatigue, and enhance recovery. However, the molecular mechanisms of its effects on exercise capacity, especially during the early stages of adaptation in physically inactive individuals, remain unclear. Methods: Male 8-week-old C57BL/6 J mice were provided with purified water or HRW for 1, 2, 4,
In VitroHighlightedMolecular Hydrogen Protects Human Melanocytes from Oxidative Stress by Activating Nrf2 SignalingMHID-7135279PMID: 345586532020Journal of Investigative DermatologyWei Fang, Luyan Tang, Guizhen Wang, Jinran Lin, Wanqing Liao, Weihua Pan, et al.Oxidative stress is proven to be critical for the initiation and progression of vitiligo. Molecular hydrogen (H2) possesses potent antioxidant activity and has been shown to protect against various oxidative stresserelated diseases. In this study, we first investigated the effects and mechanisms of H2 in human melanocytes damaged by hydrogen peroxide. We initially found that H2 reduced intracellula
