Clinical TrialHighlightedHydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkersMHID-9740359PMID: 345320232021Food Science & NutritionNikola Todorovic, Dragana Zanini, Valdemar Stajer, Darinka Korovljev, Jelena Ostojic, Sergej M OstojicThe main aim of this randomized-controlled cross-over interventional trial was to assess the acute effects of taking a single dose of hydrogen-rich water (HRW), and compare it with caffeine, HRW plus caffeine, and control water, for alertness, brain metabolism, brain and oxygen saturation, and self-reported adverse events in healthy men and women who were habitual coffee drinkers and were sleep-de