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Animal StudyIn VitroHighlighted

Molecular hydrogen inhibits lipopolysaccharide/interferon c-induced nitric oxide production through modulation of signal transduction in macrophages

MHID-1458727PMID: 217232542011Biochemical and Biophysical Research Communications

Tomohiro Itoh, Nanako Hamada, Riyako Terazawa, Mikako Ito, Kinji Ohno, Masatoshi Ichihara, et al.

Molecular hydrogen has been reported to be effective for a variety of disorders and its effects have been ascribed to the reduction of oxidative stress. However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. In the present study, we examined the hydrogen effects on lipopolysaccharide/interferon c LPS/IFNc-induced nitric ox