Clinical TrialHighlightedHydrogen gas inhalation prior to high-intensity training reduces attenuation of nitric oxide bioavailability in male rugby playersMHID-9198954PMID: 397039112024PeerJYuqi Zhao, Chaoqun Li, Shi Zhou, Zhiguang Xu, Xin Huang, Li WenBackground: Inhalation of hydrogen gas (H2) as an antioxidant supplement may alleviate exercise-induced oxidative damage and protect post-exercise hydrogen peroxide signaling, which may help mediate beneficial exercise adaptation. The aims of this study were to determine the effects of H2 inhalation on plasma nitric oxide (NO) level and its synthesis precursor in professional athletes. Methods: A