Clinical TrialHighlightedEffect of hydrogen–oxygen inhalation on sleep disorders and abnormal mood: a single-blind, randomized controlled trialMHID-9166764PMID: 408269302025Medical Gas ResearchYu Hong Gao, Jun Chen, Hua Zhong, Qiang ZhaoSleep disorders are associated with various chronic diseases. While hydrogen has anti-inflammatory, antioxidant, and antifibrotic effects and has potential applications in disease management, its impact on sleep disorders remains unclear. This single-blind, randomized controlled clinical trial from September 2022 to July 2023 at the Second Medical Center of the PLA General Hospital and the Affilia
Clinical TrialAnimal StudyHighlightedA novel intervention of molecular hydrogen on the unbalance of the gut microbiome in opioid addiction: Experimental and human studiesMHID-3437190PMID: 391167822024Biomedicine & PharmacotherapyBing Xie, Yong Wang, Yun Lu, Mengmeng Wang, Rongji Hui, Hailei Yu, et al.The gut-brain axis mediates the interaction pathway between microbiota and opioid addiction. In recent years, many studies have shown that molecular hydrogen has therapeutic and preventive effects on various diseases. This study aimed to investigate whether molecular hydrogen could serve as pharmacological intervention agent to reduce risks of reinstatement of opioid seeking and explore the mechan