Animal StudyHighlightedHydrogen-rich water reduces vascular dysfunction in a mouse model of sleep apneaMHID-65602132024Yuxi WeiObstructive sleep apnea (OSA) is a chronic condition characterized by recurrent upper airway collapse during sleep, leading to chronic intermittent hypoxia (CIH) that can cause oxidative stress and chronic inflammation that lead to cardiovascular disease (CVD). Although continuous positive airway pressure (CPAP) treatment is the gold standard for OSA treatment, it has little or no benefit in reduc
In VitroMolecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesisMHID-7973359PMID: 284674972017PLOS ONEYayoi Murakami, Masafumi Ito, Ikuroh OhsawaInhalation of molecular hydrogen (H2) gas ameliorates oxidative stress-induced acute injuries in the brain. Consumption of water nearly saturated with H2 also prevents chronic neurodegenerative diseases including Parkinson’s disease in animal and clinical studies. However, the molecular mechanisms underlying the remarkable effect of a small amount of H2 remain unclear. Here, we investigated the ef
Animal StudyHighlightedPreventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat DietMHID-6252416PMID: 280987682017NutrientsToshiki Yoneda, Takaaki Tomofuji, Muneyoshi Kunitomo, Daisuke Ekuni, Koichiro Irie, Tetsuji Azuma, et al.Obesity induces gingival oxidative stress, which is involved in the progression of alveolar bone resorption. The antioxidant effect of hydrogen-rich water may attenuate gingival oxidative stress and prevent alveolar bone resorption in cases of obesity. We examined whether hydrogen-rich water could suppress gingival oxidative stress and alveolar bone resorption in obese rats fed a high-fat diet. Ma
