Mechanisms ReviewHighlightedSaturated hydrogen saline ameliorates lipopolysaccharide-induced acute lung injury by reducing excessive autophagy (Review)MHID-2497534PMID: 285968082017Experimental and Therapeutic MedicineYIMING LIU, Jin ZhangThe pathogenesis of acute lung injury (ALI) induced by lipopolysaccharide (LPS) involves excessive pulmonary inflammation and oxidative stress. In turn, autophagy is associated with inflammatory diseases and organ dysfunction, and studies have demonstrated that LPS treatment may trigger autophagy. Thus, excessive autophagy may stimulate the strong inflammatory response observed in the development
Animal StudyMolecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and aopotosisMHID-20640112012ShockKeliang Xie, Yonghao Yu, Yi Huang, Lina Zheng, Jipeng Li, Hongguang Chen, et al.Acute lung injury (ALI) is still a leading cause of morbidity and mortality in critically ill patients. Recently, our and other studies have found that hydrogen gas (H2) treatment can ameliorate the lung injury induced by sepsis, ventilator, hyperoxia, and ischemia-reperfusion. However, the molecular mechanisms by which H2 ameliorates lung injury remain unclear. In the current study, we investigat
