Animal StudyHighlightedProtective effect of hydrogen-rich water on spermatogenesis in high-fat diet obese ratsMHID-6979663PMID: 401889722025Toxicology and Applied PharmacologyMohammad Hossein Rigi, Seyyedeh Zahra Asghari, Elaheh Eshtad, Seyedeh Elnaz Nazari, Akram Aminian, Khatereh Kharazmi, et al.Obesity can impair spermatogenesis by various mechanisms such as decreased sperm concentration and increased oxidative DNA damage. Hydrogen-rich water (HRW) possesses therapeutic antioxidant properties that may help offer protection to sperm. This study aimed to investigate the therapeutic potential of HRW on spermatogenesis dysfunction in rats with high-fat diet (HFD)-induced obesity. In this exp
Animal StudyHighlightedHydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft modelMHID-0513892PMID: 351161142022World Journal of Gastrointestinal OncologyFereshteh Asgharzadeh, Alex Tarnava, Asma Mostafapour, Majid Khazaei, Tyler W. LeBaronBackground: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in the world. Tumor removal remains the preferred frontline treatment; however, effective non-surgical interventions remain a high priority. 5-fluorouracil (5-FU) is a widely used chemotherapy agent, and molecular hydrogen (H2) has been re- cognized for its antioxidant and anti-inflammatory effects, with resear