Literature ReviewAnimal StudyIn VitroHighlightedBENEFICIAL EFFECTS OF HYDROGEN IN THE CNS AND A NEW BRAIN-STOMACH INTERACTIONMHID-45285932014European Journal of Neurodegenerative DiseasesMami Noda, M. Ito, I. Ohsawa, K. OhnoA new medical gas, molecular hydrogen (H2), has been reported to be effective for a variety of disorders and clinical trials have shown promising results. Though the precise mechanism is still unknown, it is obvious that H2 has multiple effects. The first prominent effect of H2 was as antioxidant or reactive oxygen species (ROS)-scavenger, though it blocks only hydroxyl radicals (•OH), which are t
Animal StudyHighlightedHydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson’s DiseaseMHID-8852067PMID: 197896282009PLoS ONEKyota Fujita, Toshihiro Seike, Noriko Yutsudo, Mizuki Ohno, Hidetaka Yamada, Hiroo Yamaguchi, et al.It has been shown that molecular hydrogen (H2) acts as a therapeutic antioxidant and suppresses brain injury by buffering the effects of oxidative stress. Chronic oxidative stress causes neurodegenerative diseases such as Parkinson’s disease (PD). Here, we show that drinking H2-containing water significantly reduced the loss of dopaminergic neurons in PD model mice using both acute and chronic adm
