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Literature ReviewAnimal StudyIn VitroHighlighted

BENEFICIAL EFFECTS OF HYDROGEN IN THE CNS AND A NEW BRAIN-STOMACH INTERACTION

MHID-45285932014European Journal of Neurodegenerative Diseases

Mami Noda, M. Ito, I. Ohsawa, K. Ohno

A new medical gas, molecular hydrogen (H2), has been reported to be effective for a variety of disorders and clinical trials have shown promising results. Though the precise mechanism is still unknown, it is obvious that H2 has multiple effects. The first prominent effect of H2 was as antioxidant or reactive oxygen species (ROS)-scavenger, though it blocks only hydroxyl radicals (•OH), which are t

Animal StudyHighlighted

Oral ‘hydrogen water’ induces neuroprotective ghrelin secretion in mice

MHID-1568601PMID: 242536162013Scientific Reports

Akio Matsumoto, Megumi Yamafuji, Tomoko Tachibana, Yusaku Nakabeppu, Mami Noda, Haruaki Nakaya

The therapeutic potential of molecular hydrogen (H2) is emerging in a number of human diseases and in their animal models, including in particular Parkinson’s disease (PD). H2 supplementation of drinking water has been shown to exert disease-modifying effects in PD patients and neuroprotective effects in experimental PD model mice. However, H2 supplementation does not result in detectable changes