Animal StudyIn VitroHighlightedHydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn ratsMHID-7372149PMID: 268455012016Yukako Muramatsu, MD, Mikako Ito, PhD, Takahiro Oshima, Seiji Kojima, MD, PhD, Kinji Ohno, MD, PhDBronchopulmonary dysplasia (BPD) is characterized by developmental arrest of the alveolar tissue. Oxidative stress is causally associated with development of BPD. The effects of hydrogen have been reported in a wide range of disease models and human diseases especially caused by oxidative stress. We made a rat model of BPD by injecting lipopolysaccharide (LPS) into the amniotic fluid at E16.5. The
