Scientific Articles

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Observational StudyHighlighted

Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium (HRCC) capsules in patients with metabolic syndrome: a prospective case series study

MHID-0293642PMID: 375214102023Frontiers in Nutrition

Szu-Han Chiu, Frank L. Douglas, Jia-Ru Chung, Kuang-Yih Wang, Chao-Fang Chu, Hsia-Yun Chou, et al.

Background: Metabolic syndrome is characterized by a cluster-like occurrence of conditions such as hypertension, hyperglycaemia, elevated low-density lipoprotein (LDL) cholesterol or triglycerides (TG) and high visceral fat. Metabolic syndrome is linked to the build-up of plaque within the artery, which leads to disorders of the circulatory, nervous and immune systems. A variety of treatments targ

Chemical/Physicochemical StudyHighlighted

Incorporation of hydrogen into the packaging atmosphere protects the nutritional, textural and sensorial freshness notes of strawberries and extends shelf life

MHID-3839513PMID: 361933472022Journal of Food Science and Technology

Duried Alwazeer, Nur Özkan

Strawberries are known for their high perishability and short shelf life. The effects of incorporating hydrogen gas into sealed packaging on the quality and shelf life of strawberries were evaluated. Fruits were packaged under reducing atmosphere [RAP1 (5% CO2, 4% H2, 91% N2) and RAP2 (10% CO2, 4% H2, 86% N2)], modified atmosphere [MAP1 (5% CO2, 95% N2) and MAP2 (10% CO2, 90% N2)], and control, fol

Animal StudyIn VitroHighlighted

Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice

MHID-5929908PMID: 191486452009Cancer Chemotherapy and Pharmacology

Naomi Nakashima-Kamimura, Takashi Mori, Ikuroh Ohsawa, Sadamitsu Asoh, Shigeo Ohta

Purpose: Cisplatin is a widely used anti-cancer drug in the treatment of a wide range of tumors; however, its application is limited by nephrotoxicity, which is affected by oxidative stress. We have reported that molecular hydrogen (H(2)) acts as an efficient antioxidant (Ohsawa et al. in Nat Med 13:688-694, 2007). Here we show that hydrogen efficiently mitigates the side effects of cisplatin by r