Clinical TrialHighlightedPilot Feasibility and Safety Study of Hydrogen Gas Inhalation in Locally Advanced Head and Neck Cancer PatientsMHID-6306651PMID: 394936772024OncoTargets and TherapyImjai Chitapanarux, Wimrak Onchan, Somvilai Chakrabandhu, Pooriwat Muangwong, Narongchai Autsavapromporn, Tapanut Ariyanon, et al.Hydrogen (H2) gas inhalation might alleviate acute radiotherapy toxicities by scavenging free radicals produced by ionizing radiation and anti-inflammatory properties. This study aimed to investigate the feasibility and safety of H2 gas inhalation during concurrent chemoradiotherapy (CCRT) in patients with locally advanced head and neck cancer (LAHNC). Patients and Methods: We designed a pilot pro
Human StudyLiterature ReviewAnimal StudyHydrogen therapy as a potential therapeutic intervention in heart disease: from the past evidence to future applicationMHID-3562676PMID: 372693852023Cellular and Molecular Life SciencesKwannapas Saengsin, Rekwan Sittiwangkul, Siriporn C. Chattipakorn, Nipon ChattipakornCardiovascular disease is the leading cause of mortality worldwide. Excessive oxidative stress and inflammation play an important role in the development and progression of cardiovascular disease. Molecular hydrogen, a small colorless and odorless molecule, is considered harmless in daily life when its concentration is below 4% at room temperature. Owing to the small size of the hydrogen molecule,
