Literature Review
MHID-3242181PMID: 405693542025Molecular Biology Reports
Yong Ye, Zi-hang Yu, Liang Nie, Bin Lu, Guo Mu
Pyroptosis, a highly inflammatory programmed cell death pathway, drives pathogenesis in numerous diseases through gasdermin-mediated membrane pore formation and massive cytokine release. While conventional anti-inflammatory therapies show limited efficacy, hydrogen emerges as a novel therapeutic agent with unique pyroptosis-regulatory capabilities. This review establishes a comprehensive mechanist
Literature Review
MHID-8534460PMID: 351878852022Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)
Zhiling Fu, Jin Zhang
Molecular hydrogen exerts biological effects on nearly all organs. It has anti-oxidative, anti-inflammatory, and anti-aging effects and contributes to the regulation of autophagy and cell death. As the primary organ for gas exchange, the lungs are constantly exposed to various harmful environmental irritants. Short- or long-term exposure to these harmful substances often results in lung injury, ca
Animal StudyIn VitroHighlighted
MHID-4778348PMID: 303151732018Nature Communications
Penghe Zhao, Zhaokui Jin, Qian Chen, Tian Yang, Danyang Chen, Jin Meng, et al.
By delivering the concept of clean hydrogen energy and green catalysis to the biomedical field, engineering of hydrogen-generating nanomaterials for treatment of major diseases holds great promise. Leveraging virtue of versatile abilities of Pd hydride nanomaterials in high/stable hydrogen storage, self-catalytic hydrogenation, near-infrared (NIR) light absorption and photothermal conversion, here
Animal StudyIn Vitro
MHID-5661317PMID: 223730562011BMC Proceedings
Sanetaka Shirahata, Takeki Hamasaki, Keisuke Haramaki, Takuro Nakamura, Masumi Abe, Hanxu Yan, et al.
Electrochemically reduced water (ERW) contains a lot of hydrogen molecule (H2) and scavenges reactive oxygen species (ROS) to protect DNA from oxidative damage [1]. ERW also contains small amounts of Pt nanoparticles (NPs) and elongates the lifespan of C. elegans [2]. Pt NPs are newly recognized multi-functional ROS scavengers [3]. ERW exhibits anti-diabetes effects in vitro and in vivo [4-6][7].
