Animal StudyIn VitroHighlightedSequential hydrogen-release implant for promoting the soft tissue integration through immunomodulatory and pro-remodeling couplingMHID-5401653PMID: 413343742026Bioactive MaterialsYue Yuan, Zishuo Hou, Miaomiao Chen, Jingwei Yu, Minghao Zhou, Jiaxin Kang, et al.The weaker soft tissue integration around implants compared to natural teeth poses a substantial challenge to the long-term success of implants. To enhance soft tissue integration, we develop an on-demand and long-lasting H2-releasing implant to achieve precise sequential regulation of the soft tissue integration through immunomodulation and pro-remodeling coupling. In the inflammatory phase, the
Animal StudyHighlightedPreventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat DietMHID-6252416PMID: 280987682017NutrientsToshiki Yoneda, Takaaki Tomofuji, Muneyoshi Kunitomo, Daisuke Ekuni, Koichiro Irie, Tetsuji Azuma, et al.Obesity induces gingival oxidative stress, which is involved in the progression of alveolar bone resorption. The antioxidant effect of hydrogen-rich water may attenuate gingival oxidative stress and prevent alveolar bone resorption in cases of obesity. We examined whether hydrogen-rich water could suppress gingival oxidative stress and alveolar bone resorption in obese rats fed a high-fat diet. Ma
