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Literature Review

The Effects of Molecular Hydrogen Therapies on Fertility

MHID-61283312023SciBase Clinical and Medical Case Reports

Grace Russell, Alexander Nenov

Human reproductive health is an integral part of personal well-being that can markedly impact upon individuals, couples, families and the wider society. It is estimated that infertility affects 13 to 15% of the world’s population and with parents often deciding to delay planning for pregnancy until later in life, age-related concerns about the viability of female oocytes, in partic ular, are at th

Systematic ReviewHighlighted

A Systematic Review of Molecular Hydrogen Therapy in Cancer Management

MHID-3427886PMID: 373542432023Asian Pacific Journal of Cancer Prevention

Muhammad Nooraiman Zufayri Mohd Noor, Adlin Sofea Alauddin, Yin How Wong, Chung Yeng Looi, Eng Hwa Wong, Priya Madhavan, et al.

Background: Cancer remains a challenging target to cure, with present therapeutic methods unable to exhibit restorative outcomes without causing severe negative effects. Molecular hydrogen (H2) has been reported to be a promising adjunctive therapy for cancer treatment, having the capability to induce anti-proliferative, anti-oxidative, pro-apoptotic and anti-tumoural effects. This review summaris

Literature ReviewHypothesis

Molecular hydrogen therapies and the benefits for menopausal and perimenopausal women: An aphoristic review

MHID-74012472022GSC Biological and Pharmaceutical Sciences

Grace Russell, Alexander Nenov

Women account for half of the global population, yet, when applying of the principles of legislation to women's health and gender-based research there is a void pertaining to women-specific healthcare as they age. Hydrogen therapies such as oxy-hydrogen (HHO, H2/O2) inhalation act as a novel, non-toxic, antioxidant and anti-inflammatory compounds, with clinical and empirical research confidently s

Animal StudyIn VitroHighlighted

Therapeutic potential of molecular hydrogen in ovarian cancer

MHID-18249022018Translational Cancer Research

Lei Shang, Fei Xie, Jiala Li, Yating Zhang, Mengyu Liu, Pengxiang Zhao, et al.

Background: To investigate the potential effects of molecular hydrogen on ovarian cancer. Methods: The in vivo study was performed using Hs38.T xenografted BALB/c nude mice. The mean tumor volume was monitored during 6 weeks of hydrogen inhalation. Immunohistochemistry (IHC) staining was performed to determine the Ki67 and CD34 expression. The in vitro effects of molecular hydrogen on proliferati

Animal StudyHighlighted

Hydrogen-rich saline attenuates chemotherapy-induced ovarian injury via regulation of oxidative stress

MHID-9762050PMID: 266686282015Experimental and Therapeutic Medicine

Xiaoyin Meng, Hongguang Chen, Guolin Wang, Yonghao Yu, Keliang Xie

Hydrogen has been reported to exert a therapeutic effect in several diseases due to its antioxidative, anti‑inflammatory and anti‑apoptotic properties. The aim of the present study was to investigate whether hydrogen‑rich saline treatment could attenuate ovarian damage induced by cisplatin. A total of 240 adult, virgin, female Sprague Dawley rats, weighing 180‑220 g, were randomly divided into fou