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Animal StudyIn VitroHighlighted

Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis

MHID-89507332012Medical Science Monitor

Yanyong Yang, Bailong Li, Cong Liu, Yunhai Chuai, Jixiao Lei, Fu Gao, et al.

Background: Radiation often causes depletion of immunocytes in tissues and blood, which results in immuno suppression. Molecular hydrogen (H2) has been shown in recent studies to have potential as a safe and effective radioprotective agent through scavenging free radicals. This study was designed to test the hypothesis that H2 could protect immunocytes from ionizing radiation (IR). Material/Metho

Animal Study

Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and aopotosis

MHID-20640112012Shock

Keliang Xie, Yonghao Yu, Yi Huang, Lina Zheng, Jipeng Li, Hongguang Chen, et al.

Acute lung injury (ALI) is still a leading cause of morbidity and mortality in critically ill patients. Recently, our and other studies have found that hydrogen gas (H2) treatment can ameliorate the lung injury induced by sepsis, ventilator, hyperoxia, and ischemia-reperfusion. However, the molecular mechanisms by which H2 ameliorates lung injury remain unclear. In the current study, we investigat

Animal StudyHighlighted

Hydrogen-Rich Saline Protects Myocardium Against Ischemia/Reperfusion Injury in Rats

MHID-7407969PMID: 195968252009Experimental Biology and Medicine

QIANG SUN, ZHIMIN KANG, JIANMEI CAI, WENWU LIU, YUN LIU, John H Zhang, et al.

Protective effect of hydrogen (H2) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This study was designed to test the hypothesis that hydrogen-rich saline (saline saturated with molecular hydrogen), which is easy to use, induces cardioprotection against ischemia (30 min) and reperfusion (24 h) injury in rats. Adult male Sprague-Dawley rats underwent 30-min occlu