Clinical TrialHighlightedOpen-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathiesMHID-2481572PMID: 221466742011Medical Gas ResearchMikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito, Kinji OhnoBackground: Molecular hydrogen has prominent effects on more than 30 animal models especially of oxidative stress-mediated diseases and inflammatory diseases. In addition, hydrogen effects on humans have been reported in diabetes mellitus type 2, hemodialysis, metabolic syndrome, radiotherapy for liver cancer, and brain stem infarction. Hydrogen effects are ascribed to specific radical-scavenging
Animal StudyIn VitroAnti-diabetes effect of water containing hydrogen molecule and Pt nanoparticlesMHID-5661317PMID: 223730562011BMC ProceedingsSanetaka Shirahata, Takeki Hamasaki, Keisuke Haramaki, Takuro Nakamura, Masumi Abe, Hanxu Yan, et al.Electrochemically reduced water (ERW) contains a lot of hydrogen molecule (H2) and scavenges reactive oxygen species (ROS) to protect DNA from oxidative damage [1]. ERW also contains small amounts of Pt nanoparticles (NPs) and elongates the lifespan of C. elegans [2]. Pt NPs are newly recognized multi-functional ROS scavengers [3]. ERW exhibits anti-diabetes effects in vitro and in vivo [4-6][7].
