Animal StudyHighlighted
MHID-1488636PMID: 192522952009Biological & Pharmaceutical Bulletin
Kyu Jae LEE, Dan JIN, Byung Soo CHANG, Yung Chien TENG, Dong Heui KIM
Electrolyzed reduced water (ERW) is widely used for drinking by people in Asia. The purpose of this study was to examine the immunological effect of ERW on the immunity of animals by supplying ERW to C57BL/6 mice infected with Echinostoma hortense metacercariae. In the non-infected groups, interleukin (IL)-4 (p0.001), IL-5, IL-10, IL-1b, tumor necrosis factor (TNF)-a and immunoglobulin (Ig) A exp
Animal StudyHighlighted
MHID-3088793PMID: 193565982009Neuroscience Letters
Yuan Fu, Mikako Ito, Yasunori Fujita, Masafumi Ito, Masatoshi Ichihara, Akio Masuda, et al.
Molecular hydrogen serves as an antioxidant that reduces hydroxyl radicals, but
not the other reactive oxygen and nitrogen species. In the past year, molecular hydrogen
has been reported to prevent or ameliorate eight diseases in rodents and one in human
associated with oxidative stress. In Parkinson’s disease, mitochondrial dysfunction and
the associated oxidative stress are major causes of dopam
Animal StudyHighlighted
MHID-6761448PMID: 185630582009Neuropsychopharmacology
Kazufumi Nagata, Naomi Nakashima-Kamimura, Toshio Mikami, Ikuroh Ohsawa, Shigeo Ohta
We have reported that hydrogen (H2) acts as an efficient antioxidant by gaseous rapid diffusion. When water saturated with hydrogen (hydrogen water) was placed into the stomach of a rat, hydrogen was detected at several mM level in blood. Because hydrogen gas is unsuitable for continuous consumption, we investigated using mice whether drinking hydrogen water ad libitum, instead of inhaling hydroge
Animal StudyIn VitroHighlighted
MHID-7700658PMID: 174860892007Nature Medicine
Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi, Megumi Watanabe, Kiyomi Nishimaki, Kumi Yamagata, et al.
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious damage to tissues, and persistent oxidative stress is accepted as one of the causes of many common diseases including cancer. We show here that hydrogen (H2) has potential as an antioxidant in preventive and therapeutic applications. We induced acute oxidative stress in cultured cells by three independent methods.
