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Animal StudyHighlighted

Molecular Hydrogen Improves Blueberry Main Fruit Traits via Metabolic Reprogramming

MHID-5192112PMID: 407333742025Plants

Longna Li, Jiaxin Gong, Ke Jiang, Liqin Huang, Lijun Gan, Yan Zeng, et al.

Fruit yield and quality improvement are challenges for researchers and farmers. This study reveals that the main fruit traits of blueberry (Vaccinium ashei ‘Bluegem’) were significantly improved after hydrogen (H2)-based irrigation, assessed by the increased single fruit weight (14.59 ± 6.66%) and fruit equatorial diameter (4.19 ± 2.39%), decreased titratable acidity, increased solid–acid and suga

Literature ReviewHighlighted

Hydrogen in Agriculture: A Technological Revolution From Soil to Table

MHID-46251652025Modern Agriculture

Yu Dai

Hydrogen has emerged as a pivotal element poised to revolutionise agricultural technology. Its demonstrated potential to enhance soil quality, stimulate crop growth, and elevate agricultural productivity has garnered substantial scientific interest. This paper examines the historical evolution and contemporary applications of hydrogen in agriculture, analyses future prospects and challenges, and u

In VivoHighlighted

Regulation of hydrogen rich water on strawberry seedlings and root endophytic bacteria under salt stress

MHID-2254695PMID: 396409892024Frontiers in Plant Science

Renyuan Wang, Xijia Yang, Yaowei Chi, Xia Zhang, Xianzhong Ma, Dan Zhang, et al.

Salt stress could lead to plant growth barriers and crop yield reduction. Strawberries are sensitive to salt stress, and improving salt tolerance is important for strawberry production. This study aimed to explore the potential of hydrogen-rich water (HRW) to enhance salt tolerance in strawberries. Through pot experiments, we investigated how HRW affects plant growth, ion absorption, osmotic stres

Literature ReviewHighlighted

The Effects of Molecular Hydrogen on Plant Physiology and Metabolism: An Overview

MHID-6653093PMID: 258736622024Journal of Plant Physiology and Metabolism

John T. Hancock

Gaseous hydrogen (H2) has emerged as a molecule that has a significant influence on the growth and development of plants, particularly if they are under stress. Often research has shown the ameliorating effects of H2 during drought, in the presence of heavy metals or salt, or during UV light irradiation. Postharvest, H2 has been shown to increase the quality of fruits and vegetables during storage

Literature ReviewHighlighted

The Early History of Hydrogen and Other Gases in Respiration and Biological Systems: Revisiting Beddoes, Cavallo, and Davy

MHID-86080102023Oxygen

John T. Hancock, Tyler W. LeBaron

In 2007 a paper in Nature Medicine sparked a new wave of interest in the use of molecular hydrogen (H2) for medical treatments. Since then there has been a flurry of papers looking at a range of medical aspects, from neurodegenerative disease to sports injuries. Several methods of application have been developed, including breathing the gas, or making a hydrogen-rich solution that can be ingested,

In VitroPlant StudyHighlighted

H2 supplied via ammonia borane stimulates lateral root branching via phytomelatonin signaling

MHID-7645260PMID: 379440262023Plant Physiology

Yueqiao Wang, Shanshan Jin, Ziyu Liu, Genmei Chen, Pengfei Cheng, Longna Li, et al.

A reliable and stable hydrogen gas (H2) supply will benefit agricultural laboratory and field trials. Here, we assessed ammonia borane (AB), an efficient hydrogen storage material used in the energy industry, and determined its effect on plant physiology and the corresponding mechanism. Through hydroponics and pot experiments, we discovered that AB increases tomato (Solanum lycopersicum) lateral r

Chemical/Physicochemical StudyHighlighted

Incorporation of hydrogen into the packaging atmosphere protects the nutritional, textural and sensorial freshness notes of strawberries and extends shelf life

MHID-3839513PMID: 361933472022Journal of Food Science and Technology

Duried Alwazeer, Nur Özkan

Strawberries are known for their high perishability and short shelf life. The effects of incorporating hydrogen gas into sealed packaging on the quality and shelf life of strawberries were evaluated. Fruits were packaged under reducing atmosphere [RAP1 (5% CO2, 4% H2, 91% N2) and RAP2 (10% CO2, 4% H2, 86% N2)], modified atmosphere [MAP1 (5% CO2, 95% N2) and MAP2 (10% CO2, 90% N2)], and control, fol

Literature ReviewHighlighted

Molecular Hydrogen: Is This a Viable New Treatment for Plants in the UK?

MHID-8010762PMID: 348346332021Plants

John T. Hancock, Tyler W. LeBaron, Jennifer May, Adam Thomas, Grace Russell

Despite being trialed in other regions of the world, the use of molecular hydrogen (H2) for enhanced plant growth and the postharvest storage of crops has yet to be widely accepted in the UK. The evidence that the treatment of plants and plant products with H2 alleviates plant stress and slows crop senescence continues to grow. Many of these effects appear to be mediated by the alteration of the a

In VitroOtherHighlighted

Hydrogen Evolution and Absorption Phenomena in the Plasma Membrane of Vigna radiata and Capsicum annuum

MHID-32438852021Journal of Plant Growth Regulation

Xin Zhang, Fei Xie, Zhao Zhang, Yao Mawulikplimi Adzavon, Zehua Su, Qinghui Zhao, et al.

Molecular hydrogen has been shown to exert beneficial effects on plant growth and abiotic stress tolerance, however, the exact mechanism has not yet been fully elucidated. H2 is able to diffuse directly across the plasma membrane, which is the first barrier between H2 and cells. It is possible that H2 may exert its biological effects on plant cells by interacting with PM. Hydrogenases can catalyze

In VitroEx VivoHighlighted

Hydrogen evolution and absorption phenomena in plasma membrane of higher plants

MHID-98806872020bioRxiv

Xin Zhang, Zhao Zhang, Zehua Su, Qinghui Zhao, Tyler W. LeBaron, Qinjian Li, et al.

Molecular hydrogen (H2) exhibits a wide breadth of botanical effects especially in improving the resistance to abiotic stress. However, the primary target is not clear. Bidirectional hydrogenases have been well studied in microbes and alga, but there is a paucity of research in higher plants. Here, we used real-time spectrophotometry, gas chromatography and H2 sensor to detect the H2-evolving and

Literature Review

Molecular hydrogen: a preventive and therapeutic medical gas for various diseases

MHID-3874815PMID: 292542782017Oncotarget

Li Ge, Ming Yang, Na-Na Yang, Xin-Xin Yin, Wen-Gang Song

Since the 2007 discovery that molecular hydrogen (H2) has selective antioxidant properties, multiple studies have shown that H2 has beneficial effects in diverse animal models and human disease. This review discusses H2 biological effects and potential mechanisms of action in various diseases, including metabolic syndrome, organ injury, and cancer; describes effective H2 delivery approaches; and s

Literature ReviewHighlighted

Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles

MHID-7479916PMID: 264839532015Medical Gas Research

Masatoshi Ichihara, Sayaka Sobue, Mikako Ito, Masafumi Ito, Masaaki Hirayama, Kinji Ohno

Therapeutic effects of molecular hydrogen for a wide range of disease models and human diseases have been investigated since 2007. A total of 321 original articles have been published from 2007 to June 2015. Most studies have been conducted in Japan, China, and the USA. About three-quarters of the articles show the effects in mice and rats. The number of clinical trials is increasing every year. I

Plant Study

Molecular Hydrogen Is Involved in Phytohormone Signaling and Stress Responses in Plants

MHID-7838829PMID: 239510752013PLoS ONE

Jiqing Zeng, Mingyong Zhang, Xuejun Sun

Molecular hydrogen (H2) metabolism in bacteria and algae has been well studied from an industrial perspective because H2 is viewed as a potential future energy source. A number of clinical trials have recently reported that H2 is a therapeutic antioxidant and signaling molecule. Although H2 metabolism in higher plants was reported in some early studies, its biological effects remain unclear. In th

Plant StudyHighlighted

Hydrogen gas acts as a novel bioactive molecule in enhancing plant tolerance to paraquat-induced oxidative stress via the modulation of heme oxygenase-1 signalling system

MHID-6657679PMID: 230947982012Plant, Cell and Environment

Qijiang Jin, Weiti Cui, Bin Han, Yanjie Xie, Kaikai Zhu, Wenbiao Shen

Hydrogen gas (H2) was recently proposed as a novel antioxidant and signalling molecule in animals. However, the physiological roles of H2 in plants are less clear. Here, we showed that exposure of alfalfa seedlings to paraquat stress increased endogenous H2 production. When supplied with exogenous H2 or the heme oxygenase-1 (HO-1)-inducer hemin, alfalfa plants displayed enhanced tolerance to oxida