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Animal StudyIn VitroHighlighted

Sonocatalytic hydrogen/hole-combined therapy for anti-biofilm and infected diabetic wound healing

MHID-3225760PMID: 370564242023National Science Review

Qingqing Xu, Shengqiang Chen, Lingdong Jiang, Chao Xia, Lingting Zeng, Xiaoqing Cai, et al.

It is a great challenge to effectively eradicate biofilm and cure biofilm-infected diseases because dense extracellular polymeric substance matrix prevents routine antibacterial agents from penetrating into biofilm. H2 is an emerging energy-regulating molecule possessing both high biosafety and high tissue permeability. In this work, we propose a concept of sonocatalytic hydrogen/hole-combined ‘in

Systematic ReviewMeta-AnalysisHighlighted

Effects of hydrogen rich water and pure water on periodontal inflammatory factor level, oxidative stress level and oral flora: a systematic review and meta-analysis

MHID-6169739PMID: 363888302022Annals of Translational Medicine

Yang Bai, Chenglong Wang, Hua Jiang, Lin Wang, Nan Li, Wei Zhang, et al.

Background: Hydrogen rich water (HRW) was used as an auxiliary treatment for periodontitis and peri-implantitis due to its good antioxidant properties. However, the stability of artificially added active hydrogen was far less than that of pure natural active hydrogen, which greatly reduced active hydrogen molecules number in HRW. Meanwhile, the effect of HRW was relatively slow. Finally, long-term

In VitroHighlighted

Response of Escherichia coli to hydrogen nanobubbles: an in vitro evaluation using synchrotron infrared spectroscopy

MHID-0456102PMID: 347832272021Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)

Jinfang LU, Jin ZHENG, Yadi WANG, Jie CHENG, Xueling LI, Jun HU, et al.

Hydrogen (H2)-rich water, an apparent source of molecular H2, is an emerging functional drink with many purported benefits for human health (Yang et al., 2020; Ostojic, 2021). The preventive and therapeutic effects of H2 on various pathological processes have been intensively investigated in numerous clinical trials; it is commonly believed that the beneficial effects are mainly attributed to its