Scientific Articles

Search verified research on molecular hydrogen.

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Hypothesis

Gas as medicine: the case for hydrogen gas as a therapeutic agent for critical illness

MHID-2190797PMID: 409385202025Intensive Care Medicine Experimental

Lakhmir S. Chawla

Molecular hydrogen gas (HG), administered through inhalation or as hydrogen-rich fluids (HRF), has demonstrated antioxidant, anti-inflammatory, antiapoptotic, cytoprotective, and beneficial mitochondrial effects in critical illness. Preclinical studies and human clinical studies consistently endorse hydrogen gas as safe, with mechanisms of action linked to vital molecular pathways, such as reducti

Literature Review

Protective effects of molecular hydrogen on lung injury from lung transplantation

MHID-3527018PMID: 338995452021Experimental Biology and Medicine

Lini Quan, Bin Zheng, Huacheng Zhou

Lung grafts may experience multiple injuries during lung transplantation, such as warm ischaemia, cold ischaemia, and reperfusion injury. These injuries all contribute to primary graft dysfunction, which is a major cause of morbidity and mortality after lung transplanta- tion. As a potential selective antioxidant, hydrogen molecule (H2) protects against post- transplant complications in animal mod