HypothesisGas as medicine: the case for hydrogen gas as a therapeutic agent for critical illnessMHID-2190797PMID: 409385202025Intensive Care Medicine ExperimentalLakhmir S. ChawlaMolecular hydrogen gas (HG), administered through inhalation or as hydrogen-rich fluids (HRF), has demonstrated antioxidant, anti-inflammatory, antiapoptotic, cytoprotective, and beneficial mitochondrial effects in critical illness. Preclinical studies and human clinical studies consistently endorse hydrogen gas as safe, with mechanisms of action linked to vital molecular pathways, such as reducti
Literature ReviewProtective effects of molecular hydrogen on lung injury from lung transplantationMHID-3527018PMID: 338995452021Experimental Biology and MedicineLini Quan, Bin Zheng, Huacheng ZhouLung grafts may experience multiple injuries during lung transplantation, such as warm ischaemia, cold ischaemia, and reperfusion injury. These injuries all contribute to primary graft dysfunction, which is a major cause of morbidity and mortality after lung transplanta- tion. As a potential selective antioxidant, hydrogen molecule (H2) protects against post- transplant complications in animal mod