Literature ReviewThe On/Off History of Hydrogen in Medicine: Will the Interest Persist This Time Around?MHID-40908422023OxygenTyler W. LeBaron, Kinji Ohno, John T. HancockOver 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within the past 15 years. However, we have unknowingly benefited from H2 since the dawn of time, from H2-producing bacteria to the use of naturally occurring hydrogen-rich waters. Moreover, the first writings on the therapeutic effects of
Literature ReviewMechanisms ReviewTherapeutic Efficacy of Molecular Hydrogen: A New Mechanistic InsightMHID-7292103PMID: 310571052019Current Pharmaceutical DesignToru IshibashiBackground: Molecular hydrogen (H2) is now recognized as a therapeutic gas for the treatment of numerous diseases including neurodegenerative diseases, metabolic disorders, and inflammatory diseases. Non- polar, neutral H2 is assumed to have health benefits facilitated by its passive diffusion across the human body immediately after administration and is considered a safe therapeutic inert gas tha