Animal StudyEffects of hydrogen-rich water and ascorbic acid treatment on spontaneously hypertensive ratsMHID-7818899PMID: 352644922022Experimental AnimalsKohei Kawakami, Hiroyuki Matsuo, Takaya Yamada, Ken-ichi Matsumoto, Daigoro Sasaki, Masato NomuraHydrogen-rich water (HW) has been suggested to possess antioxidant properties of value in treatments of lifestyle diseases and for prevention of latent pathologies. To date, the potential benefits of HW against the deleterious effects of excessive salt intake and hypertension have not been investigated. Here, we first examined the effects of HW or HW supplemented with 0.1% ascorbic acid (HWA) on s
Opinion PieceMolecular hydrogen: A novel therapy for the treatment of pulmonary hypertensionMHID-8567647PMID: 261233972015The Journal of Thoracic and Cardiovascular SurgeryHarold L. Lazar, MDPatients with pulmonary arterial hypertension (PAH) are at higher risk for morbidity and mortality after all types of cardiac surgical procedures. These patients have higher incidences of hemodynamic instability, hypoxemia, and right ventricular dysfunction. Current therapy for PAH has included prostanoids, endothelial receptor antagonists, and phosphodiesterase inhibitors. Although these agents h
