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Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation

MHID-2283082PMID: 115104172001Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie / Life Sciences (Comptes Rendus Biologies)

Bouchra Gharib, Stéphane Hanna, Ould M.S. Abdallahi, Hubert Lepidi, Bernard Gardette, Max De Reggi

Molecular hydrogen reacts with the hydroxyl radical, a highly cytotoxic species produced in inflamed tissues. It has been suggested therefore to use gaseous hydrogen in a new anti-inflammatory strategy. We tested this idea, with the aid of the equipment and skills of COMEX SA in Marseille, a group who experiments with oxygen–hydrogen breathing mixtures for professional deep-sea diving. The model use